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Drug and Alcohol Studies Biological Approaches By Kim Wolff Jason White Steven Karch

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Pages
569
File size
11.74 MB
Format
Digital PDF
Category
eBook[PDF]
About this ebook
The Drug & Alcohol Studies: Biological Approaches" is a comprehensive academic text edited by Kim Wolff, Jason White, and Steven Karch. [1]
The handbook explores the biological basis of substance misuse, focusing on how drugs and alcohol interact with the human body, brain chemistry, and genetic frameworks. It serves as a vital reference for researchers, clinicians, and students studying pharmacology, addiction science, and forensic toxicology. [1, 2, 3, 4]
Core Book Structure
The text is divided into four key parts comprising 31 chapters: [1, 2]
  • Part I: Determination of Substance Misuse – Focuses on genetic and genomic factors in addiction research, investigating how individuals and different ethnic groups metabolise substances differently. [1, 2]
  • Part II: Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Patterns of Use – Details what the body does to a drug (absorption, distribution, metabolism, excretion) and how substances interact with major neurotransmitters to cause intoxication, tolerance, and dependence. [1, 2, 3]
  • Part III: Detection and Treatment of Drug and Alcohol Use – Outlines routine and state-of-the-art developments in substance detection, including post-mortem analysis, population screening, and clinical biomarkers. [1, 2]
  • Part IV: Controversies and New Approaches – Explores modern and evolving debates in the field, including legal driving limits for substances, decriminalisation, and cultural influences. [1, 2, 3]
About the Editors
The book brings together expertise from three prominent figures in addiction pharmacology and forensics:
  1. Professor Kim Wolff (King's College London): An expert in addiction science and biomarkers, awarded an MBE for her contributions to developing national drug-driving legislation and road safety policies in the UK.
  2. Professor Jason White (University of South Australia): A pharmacologist specializing in the effects of addictive drugs (specifically opioids and stimulants) who has served as the Co-Chair of the WHO Expert Committee on Drug Dependence.
  3. Dr. Steven Karch: A renowned cardiac pathologist who specialized in the effects of drug abuse on the heart, famously known for authoring The Pathology of Drug Abuse.

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