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E BOOK Biotechnology of Microbial Enzymes Production, Biocatalysis, and Industrial Applications 2nd Edition by Goutam Brahmachari

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Pages: 1,220
File size: 36.31 MB
Format: Digital PDF
Course: Biotechnology
Category: eBook[PDF]

About this ebook

The Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, edited by Goutam Brahmachari, provides a comprehensive survey of microbial enzymes, focusing on their production, molecular optimization, and role as green biocatalysts across multiple industries. [1, 2, 3]

The text covers the following key core topics and research domains:

1. Advanced Engineering & Production Technologies

Metabolic Pathway Engineering & Synthetic Biology: Strategies for manipulating natural biosynthetic pathways to build efficient cell factories and produce novel chemical structures. [1, 2]
Molecular Biology Interventions: The integration of modern molecular methodologies, including recombinant DNA technology, to enhance enzyme efficiency during industrial fermentation. [1, 2]
Directed Evolution & Rational Design: Methods for custom-tailoring enzymes to optimize their durability, substrate selectivity, and shelf life. [1, 2, 3]
Metagenomic Screening & Genomics: Techniques utilized to screen diverse environment samples and discover novel or high-yield microbial strains. [1, 2]
Extremophiles: Exploration of enzymes sourced from microbes thriving in extreme conditions (high temperature, high salinity, extreme pH), expanding their applicability to harsh industrial workflows. [1, 2]

2. Pharmaceutical & Biomedical Applications

Drug Discovery: The integration of newly discovered microbial enzyme systems to assist in modern pharmaceutical design.
Antitubercular Drug Design: Specific applications of targeted microbial systems engineered for anti-tuberculosis therapy.
Antibiotic Machinery: Deep dives into penicillin biosynthetic enzymes, penicillin acylase, and xylose reductase.
Heterogeneous Reconstruction: Structural synthesis of complex chemical scaffolds—such as fungal polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs)—for advanced drug development. [1, 2, 3]

3. Industrial, Food, and Biofuel Biocatalysis

Biofuels & Energy Production: The use of lipases and other biocatalysts for the degradation of raw materials and the processing of eco-friendly biodiesel.
Food & Feed Processing: Enzymatic biotransformations targeted at food quality, optimization, preservation, and nutrition.
Textile & Chemical Manufacturing: The utilization of amylases, peroxidases, cellulases, and laccases as cost-effective, non-toxic alternatives to harsh manufacturing chemicals. [1, 2, 3]

4. Sustainability & Environmental Bioremediation

Green Chemistry: Conducting industrial-scale chemical reactions under mild, energy-efficient, and green conditions.
Pollutant Mitigation: Deploying microbial oxidases, reductases, and transferases for environmental cleanups, waste mineralization, and biodegradation. [1, 2, 3, 4]