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Challenging Cases in Diagnostic Clinical Microbiology: Advanced Strategies and Techniques 2024th Edition by James J. Dunn, Marc Roger Couturier, Audrey N. Schuetz | eBook [pdf]

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Pages: 252
File size: 3.56 MB
Format: Digital PDF
Course: Medicine
Category: eBook[PDF]

About this ebook

Challenging Cases in Diagnostic Clinical Microbiology: Advanced Strategies and Techniques (2024th Edition) by James J. Dunn, Marc Roger Couturier, and Audrey N. Schuetz is structurally organized into major organism-based chapters. Each chapter leads with a technical review of diagnostic methodologies followed by a series of real-world, complex clinical case studies. [1, 2, 3]

The principal core topics and sections covered in the book include: [1, 2, 3]

Bacteriology and Mycobacteriology

- Methodology Overviews: Conventional culture techniques vs. culture-independent diagnostic tests (CIDT), direct specimen staining, and biochemical profiling. [1]
- Advanced Identifications: Implementation of molecular-based detection methods (such as PCR) and modern diagnostic algorithms. [1]
- Antimicrobial Susceptibility Testing (AST): Core methods used to detect microbial resistance and guide tailored clinical therapies. [1]
- Case Studies: Detailed patient case workups (Cases 1 through 16) exploring challenging or atypical bacterial and mycobacterial infections.

Virology

- Methodology Overviews: Standard frameworks in immunodiagnostics, viral culture variants, and rapid antigen tracking.
- Molecular Viral Diagnostics: Utilization of nucleic acid amplification testing (NAAT) to establish viral loads and identify challenging viral pathogens.
- Case Studies: Real-world medical scenarios (Cases 17 through 24) targeting complex differential diagnoses for viral syndromes. [1, 2, 3, 4]

Mycology

- Methodology Overviews: Comparative analysis between histopathologic examinations in tissue and isolation on solid mycological media.
- Fungal Profiles: Workflows for fast, accurate identification of hyaline molds, dimorphic fungi, and opportunistic yeasts.
- Antifungal Susceptibility: Strategic laboratory steps to map out drug resistance profiles for invasive fungal infections.
- Case Studies: Instructive case presentations outlining diagnostic pitfalls and multi-tiered testing algorithms for deep-seated or rare mycoses. [1, 2, 3, 4]

Parasitology

Methodology Overviews: Traditional microscopic examinations (such as stool ova and parasite exams) evaluated against modern molecular assay targets.
Pathogen Screening: Lab capabilities focused on detecting region-specific vs. worldwide parasitic etiologies from diverse specimen types.
Case Studies: Clinical scenarios involving intricate parasite life cycles, travel-related medical histories, and unusual presentations that complicate typical diagnostic testing. [1]