An Introduction to Medicinal Chemistry 7th Edition By Graham L. Patrick
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- 3,064
- File size
- 49.52 MB
- Format
- Digital PDF
- Course
- Education
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- eBook[PDF]
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About this ebook
The An Introduction to Medicinal Chemistry (7th Edition) by Graham L. Patrick is structured into an introductory chapter followed by five core thematic parts, mapping the entire process of how drugs are conceptualized, designed, tested, and targeted in the body. [1, 2, 3]
The text covers the following specific topics and chapters: [1]
Introductory Overview
- Chapter 1: Drugs and drug targets: an overview [1]
Parts A through E: Core Themes and Applications
The remaining chapters are organized into five comprehensive parts detailing the entire discipline: [1]
- Part A (Chapters 2–6): Drug Targets: Structure and Function – Covers the fundamental biochemistry of proteins, enzymes, receptors, signal transduction, and nucleic acids. [1, 2]
- Part B (Chapters 7–11): Pharmacodynamics and Pharmacokinetics – Explores specific molecular targets, drug interactions, and body processing, featuring a case study on statins. [1, 2, 3]
- Part C (Chapters 12–15): Drug Discovery, Design, and Development – Details lead compound discovery, optimization, and market delivery, complete with case studies on ACE inhibitors, antimalarials, and oxamniquine. [1, 2, 3, 4]
- Part D (Chapters 16–18): Tools of the Trade – Focuses on combinatorial synthesis, computer-aided design, and QSAR, including thymidylate synthase inhibitor design. [1, 2, 3]
- Part E (Chapters 19–28): Topic Areas in Medicinal Chemistry – Examines major therapeutic classes including antibacterial, antiviral, anticancer, nervous system, and cardiovascular drugs, alongside biologics and anti-ulcer agents. [1, 2]
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