Janeway’s Immunobiology 10th Edition By Kenneth Murphy, Casey Weaver, Leslie Berg
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Janeway’s Immunobiology 10th Edition By Kenneth Murphy, Casey Weaver, Leslie Berg

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2,396
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20.61 MB
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About this ebook
Janeway’s Immunobiology, 10th Edition, authored by Kenneth Murphy, Casey Weaver, and Leslie Berg, is a premier, comprehensive textbook covering advanced immunology. The text is structurally organized into five major parts: [1, 2]
Part I: An Introduction to Immunobiology and Innate Immunity
  • Basic Concepts in Immunology: Introduction to white blood cells, lymphoid organs, and foundational principles of innate vs. adaptive immunity. [1]
  • Innate Immunity (The First Lines of Defense): Surface barriers, antimicrobial peptides, and immediate physiological responses to pathogens. [1]
  • Cellular Mechanisms of Innate Immunity: Pattern recognition receptors (PRRs), the cGAS/STING pathway, phagocyte activation, and early inflammatory signaling. [1, 2]
Part II: The Recognition of Antigen
  • Antigen Recognition & Generation: Covers B-cell and T-cell receptor biochemistry, somatic recombination, V(D)J rearrangement, and MHC structure and peptide loading. [1]
Part III: The Development of Mature Lymphocyte Receptor Repertoires
  • Signaling and Development: Details intracellular signal transduction cascades, hematopoiesis, positive and negative selection, and central tolerance. [1]
Part IV: The Adaptive Immune Response
  • Immunity Dynamics: Explores T-cell mediated and humoral immune responses, integration with innate immunity, and specialized mucosal immunity. [1, 2]
Part V: The Immune System in Health and Disease
  • Pathology and Manipulation: Addresses host defense failures, including SARS-CoV-2 and HIV, allergy and hypersensitivity, autoimmunity, transplantation, and immunological manipulation like vaccines and cancer therapy. [1, 2, 3]

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Topics

Adaptive Immune Response Antigen Recognition & Generation Autoimmunity Cellular Mechanisms of Innate Immunity Development of Mature Lymphocyte Receptor Repertoires foundational principles of innate vs. adaptive immunity hypersensitivity Immune System in Health and Disease Immunity Dynamics Immunobiology and Innate Immunity immunological manipulation Innate Immunity: The First Lines of Defense ISBN-10: 0393884899 ISBN-10: 0393884910 ISBN-13: 978-0393884876 ISBN-13: 978-0393884890 ISBN-13: 978-0393884906 ISBN-13: 978-0393884913 lymphoid organs Pathology and Manipulation SARS-CoV-2 and HIV Signaling and Development transplantation white blood cells
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