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Medicinal Chemistry 2nd Edition By Norma K Dunlap, Donna M Huryn

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Document details

Pages: 483
File size: 6.85 MB
Format: Digital PDF
Course: Chemistry
Category: eBook[PDF]

About this ebook

The 2nd Edition of Medicinal Chemistry by Norma K. Dunlap and Donna M. Huryn is structured into three main parts covering the workflow of drug discovery, biological targets, and specific therapeutic applications. [1]

The complete breakdown of the topics and chapters covered in this edition includes:

Part I: Introduction to Drug Discovery

This section establishes the conceptual foundation of how drugs are identified, optimized, and brought to market. [1]

Chapter 1: Historical Perspective and Overview of Drug Discovery
Chapter 2: Drug Discovery: Hit and Lead Identification
Chapter 3: Lead Optimization: Drug-Target Interactions and the Pharmacophore
Chapter 4: Lead Optimization: Properties Optimized and Medicinal Chemistry Strategies
Chapter 5: The Process of Developing a Drug from an Optimized Lead [1]

Part II: Classes of Drug Targets

This section transitions into structural biology, examining the molecular structures and chemistry of the major biological mechanisms that drugs interact with. [1]

Chapter 6: Receptors, Ion Channels, and Transporters as Drug Targets
Chapter 7: Enzymes as Drug Targets
Chapter 8: Protein–Protein and Lipid Structure Interactions as Drug Targets
Chapter 9: DNA and RNA as Drug Targets [1]

Part III: Selected Therapeutic Areas

The final part applies the prior concepts to real-world pharmacology, looking at specific classes of drugs used to treat prominent global health conditions. [1]